Katedra i Zakład Chemii Organicznej

Najważniejsze publikacje:

1. Z. Brzozowski, J. Sławiński, A. Innocenti, C.T. Supuran, Carbonic Anhydrase Inhibitors, regioselective synthesis of novel 1-substituted 1,4-dihydro-4-oxo-3-pyridinesulfonamides and their inhibition of the human cytosolic isozymes I and II and transmembrane cancer associated isozymes IX and XII, Eur. J. Med. Chem. 45, 9 (2010) 3656-3661
2. Z. Brzozowski, J. Sławiński, F. Sączewski, A. Innocenti, C.T. Supuran, Carbonic anhydrase inhibitors: Synthesis and inhibition of the human cytosolic isozymes I and II and transmembrane isozymes IX, XII (cancer-associated) and XIV with 4-substituted 3-pyridinesulfonamides, Eur. J. Med. Chem., 45 (2010) 2396-2404
3. Z. Brzozowski, J. Sławiński, Reaction products of activated aromatic and heteroaromatic chlorides with N,N-disubstituted formamides, Synth. Commun., 40 (2010) 1639-1645
4. K. Gobis, H. Foks, Microwave-assisted synthesis of novel 4-N,N-dimethylamino- and 4-cycloamino- substituted 1,2,4-triazole-3-thiones, Heteroatom, 21, 3 (2010) 188-195
5. B. Pilarski, A. Dobkowska, H. Foks, T. Michałowski, Modelling of acid-base equilibria in binary-solvent systems: a comparative study, Talanta, 80 (2010) 1073-1080
6. Z. Brzozowski, J. Sławiński, A. Kędzia, E. Kwapisz, M. Gdaniec, Application of 3-methylthiopyrido[4,3-e]-1,4,2-dithiazine 1,1-dioxide to the synthesis of novel series of 4H-pyrido[4,3-e]-1,2,4-thiadiazine derivatives with potential biological activity, J. Heterocyclic Chem., 46, 6 (2009) 1396-1403
7. Z. Brzozowski, F. Sączewski, J. Sławiński, T. Sanchez, N. Neamati, Synthesis and anti-HIV-1 integrase activities of 3-aroyl-2,3-dihydro-1,1-dioxo-1,4,2-benzodithiazines, Eur. J. Med. Chem., 44, 1 (2009) 190-196
8. K. Gobis, H. Foks, A. Kędzia, M. Wierzbowska, Z. Zwolska, Synthesis and antibacterial activity of novel pyridine and pyrazine derivatives obtained from amidoximes, J. Heterocyclic Chem. , 46, 6 (2009) 1271-1279
9. A. Bogdanowicz, H. Foks, A. Kędzia, E. Kwapisz, Z. Zwolska, E. Augustynowicz-Kopeć, The synthesis and microbiological activity of new 4-chloropyridin-2-yl derivatives, Heterocycles, 78, 9 (2009) 2217-2231
10. H. Foks, K. Wisterowicz, A. Miszke, K. Brożewicz, K. Wiśniewska, M. Dąbrowska-Szponar, Synthesis, fungicidal and antibacterial activity of new pyridazine derivatives, Heterocycles, 78, 4 (2009) 961-975
11. W. Konieczny, M. T. Konieczny, Synthesis of thioflavanone and flavanone derivatives by cyclization of chalcones, Synthesis, 11 (2009) 1811-1814
12. M. T. Konieczny, Paweł Sowiński, Mechanism of isomerization and acid-induced transformations of 3'-hydroxy-4,4'-dimethoxy-3'-methyl-3-oxo-7,7'-bis(piperidinocarbonyloxy)-2,2-spirobi[2H,2'H,3H,3'H-benzo[b]thiophene]. Unusual equilibrium between the spiro and 3-hydroxybenzothiophene systems, Bull. Chem. Soc. Jpn., 82, 5 (2009) 600-602
13. F. Sączewski, A. Innocenti, J. Sławiński, A. Kornicka, Z. Brzozowski, E. Pomarnacka, A. Scozzafava, C. Temperini, C. T. Supuran, Carbonic anhydrase inhibitors: inhibition of human cytosolic isozymes I and II and tumor-associated isozymes IX and XII with S-substituted 4-chloro-2-mercapto-5-methyl-benzenesulfonamides, Bioorg. Med. Chem., 16, 7 (2008) 3933-3940
14. Z. Brzozowski, J. Sławiński, F. Sączewski, T. Sanchez, N. Neamati, Synthesis, anti-HIV-1 integrase, and cytotoxic activities of 4-chloro-N-(4-oxopyrimidin-2-yl)-2-mercaptobenzenesulfonamide derivatives, Eur. J. Med. Chem., 43 (2008) 1188-1198
15. A. Miszke, H. Foks, K. Brożewicz, A. Kędzia, E. Kwapisz, Z. Zwolska, The synthesis and microbiological activity of 2-mercapto-4-methoxypyridine-3-carbonitrile derivatives, Heterocycles, 75, 11 (2008) 2723-2734
16. Z. Brzozowski, F. Sączewski, J. Sławiński, Syntheses of potassium 1,1-dioxopyrido[4,3-e]-1,4,2-dithiazine-3-thiolate and its application to the synthesis of novel sulfonamides with potential biological activity, J. Heterocyclic Chem., 45, 5 (2008) 1407-1413
17. B. Saraswathyamma, I. Grzybowska, C. Orlewska, J. Radecki, W. Dehaen, K. G. Kumar, H. Radecka, Electroactive dipyrromethene-Cu(II) monolayers deposited onto gold electrodes for voltammetric determination of paracetamol, Electroanalysis, 20, 21 (2008) 2317-2323
18. I. Szymańska, M. Stobiecka, C. Orlewska, T. Rohand, D. Janssen, W. Dehaen, H. Radecka, Electroactive dipyrromethene – Cu(II) self-assembled monolayers: complexation reaction on the surface of gold electrodes, Langmuir, 24, 19 (2008) 11239-11245