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Katedra i Zakład Chemii Farmaceutycznej

Wydział Farmaceutyczny z Oddziałem Medycyny Laboratoryjnej

AKTYWNOŚCI PUBLIKACYJNE

*Najważniejsze publikacje z ostatnich lat:

2017
  • A. Chmielewska, T. Bączek, Ligand-exchange chromatography for the chiral separations of ofloxacin enantiomers [Dokument elektroniczny], Acta Pol. Pharm. – Drug Res., 74 (2017) 1659-1665.
  • A. Synakiewicz, M. Sawicka-Żukowska, N. Adrianowska, G. Gałęzowska, J. Ratajczyk, A. Owczarzak, L. Konieczna, T. Stachowicz-Stencel, Amino acid profiles as potential biomarkers for pediatric cancers : a preliminary communication, Biomark. Med. 11 (2017) 619-627.
  • K. Ciura, A. Rutecka, P. Kawczak, J. Nowakowska. Quantitative structure-retention relationship modeling of the retention behavior of selected antipsychotic drugs in normal-phase thin-layer chromatography, JPC – J. Planar Chromatogr. Mod. TLC 30 (2017) 225-230.
  • B. Żołnowska, J. Sławiński, A. Pogorzelska, K. Szafrański, A. Kawiak, G. Stasiłojć, M. Belka, J. Zielińska, T. Bączek. Synthesis, QSAR studies, and metabolic stability of novel 2-alkylthio-4-chloro-N-(5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)benzenesulfonamide derivatives as potential anticancer and apoptosis-inducing agents, Chem. Biol. Drug Des., 90 (2017) 380-396.
  • K. Ciura, J. Nowakowska, P. Kawczak, K.E. Greber, M.J. Markuszewski, Quantitative structure-retention relationships and quantitative structure-activity relationships study of macrolide antibiotics on micellar thin layer chromatography. Acta Pol. Pharm. – Drug Res., 74 (2017) 1365-1372.
  • B. Żołnowska, J. Sławiński, A. Pogorzelska, K. Szafrański, A. Kawiak, G. Stasiłojć, M. Belka, J. Zielińska, T. Bączek, Synthesis, QSAR studies, and metabolic stability of novel 2-alkylthio-4-chloro-N-(5-oxo-4,5-dihydro-1,2,4-triazin-3-yl)benzenesulfonamide derivatives as potential anticancer and apoptosis-inducing agents, Chem. Biol. Drug Des., 90 (2017) 380-396.
  • A. Pogorzelska, J. Sławiński, B. Żołnowska, K. Szafrański, A. Kawiak, J. Chojnacki, Sz. Ulenberg, J. Zielińska, T. Bączek, Novel 2-(2-alkylthiobenzenesulfonyl)-3-(phenylprop-2-ynylideneamino)guanidine derivatives as potent anticancer agents : synthesis, molecular structure, QSAR studies and metabolic stability, Eur. J. Med. Chem. 138 (2017) 357-370.
  • N. Miękus, L. Konieczna, P. Kowiański, J. Moryś, T. Bączek, HILIC-MS rat brain analysis, a new approach for the study of ischemic attack, Transl. Neurosci. 8 (2017) 70-75.
  • I. Olędzka, P. Kowalski, A. Plenis, T. Bączek, Evaluation of various approaches to the isolation of steroid hormones from urine samples prior to FASS-MEKC analysis, Electrophoresis 38 (2017) 1632–1643.
  • K. Ciura, M. Belka, P. Kawczak, T. Bączek, M.J. Markuszewski, J. Nowakowska, Combined computational-experimental approach to predict blood-brain barrier (BBB) permeation based on “green” salting-out thin layer chromatography supported by simple molecular descriptors, J. Pharm. Biomed. Anal., 143 (2017) 214-221.
  • M. Belka, Sz. Ulenberg, T. Bączek, Fused deposition modeling enables the low-cost fabrication of porous, customized-shape sorbents for small-molecule extraction, Anal. Chem., 89 (2017) 4373-4376.
  • A. Kornicka, A. Wasilewska, J. Sączewski, A.L. Hudson, K. Boblewski, A. Lehmann, K. Gzella, M. Belka, F. Sączewski, M. Gdaniec, A. Rybczyńska, T. Bączek, 1-[(Imidazolidin-2-yl)imino]-1H-indoles as new hypotensive agents: synthesis and in vitro and in vivo biological studies, Chem. Biol. Drug Des., 89 (2017) 400-410.
  • P. Kowalski, I. Olędzka, A. Plenis, T. Bączek, Dynamic double coating, electrophoretic method with indirect detection for the simultaneous quantification of mono- and divalent cations in various water samples, Electrophoresis 38 (2017) 477-485.
  • J. Sławiński, K. Szafrański, A. Pogorzelska, B. Żołnowska, A. Kawiak, K. Macur, M. Belka, T. Bączek, Novel 2-benzylthio-5-(1,3,4-oxadiazol-2-yl)benzenesulfonamides with anticancer activity: synthesis, QSAR study, and metabolic stability, Eur. J. Med. Chem., 132 (2017) 236-248.
2016
  • N. Miękus, I. Olędzka, A. Plenis, P. Kowalski, E. Bień, A. Miękus, M.A. Krawczyk, E. Adamkiewicz-Drożyńska, T. Bączek, Determination of urinary biogenic amines’ biomarker profile in neuroblastoma and pheochromocytoma patients by MEKC method with preceding dispersive liquid-liquid microextraction, J. Chromatogr. B 1036-1037 (2016) 114-123.
  • A. Chmielewska, L. Konieczna, T. Bączek, A novel two-step liquid-liquid extraction procedure combined with stationary phase immobilized human serum albumin for the chiral separation of cetirizine enantiomers along with M and P parabens, Molecules 21 (2016) nr 12, art. 1654, s. [1-13] [Dokument elektroniczny]
  • A. Plenis, A. Frolow, N. Rekowska, I. Olędzka, P. Kowalski, E. Bień, M.A. Krawczyk, E. Adamkiewicz-Drożyńska, T. Bączek, Determination of bendamustine in human plasma and urine by LC-FL methods: application in a drug monitoring Chromatographia 79 (2016) 861-873.
  • A. Plenis, I. Olędzka, P. Kowalski, T. Bączek, Strategies for the assessment of metabolic profiles of steroid hormones in view of diagnostics and drug monitoring: analytical problems and challenges, Curr. Drug Metab., 17 (2016) 703-720.
  • A. Neumann, M. Wieczór, J. Zielińska, M. Bagiński, J. Czub, Membrane sterols modulate the binding mode of amphotericin B without affecting its affinity for a lipid bilayer, Langmuir 32 (2016) 3452-3461.
  • P. Žuvela, K. Macur, J. Jay Liu, T. Bączek, Exploiting non-linear relationships between retention time and molecular structure of peptides originating from proteomes and comparing three multivariate approaches, J. Pharm. Biomed. Anal. 127 (2016) 94-100.
  • J. Nowakowska, K. Ciura, P. Kawczak, T. Bączek, M.J. Markuszewski, Quantitative structure-retention relationships of some steroid and phenanthrene derivatives on cyano-, reversed-phase, and normal-phase thin-layer chromatography stationary phases, JPC – J. Planar Chromatogr. – Mod. TLC 29 (2016) 165-175.
  • P. Kawczak, T. Bączek, The current use of mass spectrometry in combination with other separation techniques in drug discovery arena, Med. Chem., 12 (2016) 404-411.
  • B. Żołnowska, J. Sławiński, A. Pogorzelska, K. Szafrański, A. Kawiak, G. Stasiłojć, M. Belka, Sz. Ulenberg, T. Bączek, J. Chojnacki, Novel 5-substituted 2-(aylmethylthio)-4-chloro-N-(5-aryl-1,2,4-triazin-3-yl)benzenesulfonamides: synthesis, molecular structure, anticancer activity, apoptosis-inducing activity and metabolic stability [Dokument elektroniczny], Molecules 21(6) (2016) art. 808, s. [1-27].
  • K. Ciura, P. Kowalski, J. Nowakowska, M. Markuszewski, T. Bączek, Sz. Dziomba, Sweeping of hydrophobic amines under inhomogeneous electric field and low surfactant concentration in micellar electrokinetic chromatography, Electrophoresis 37 (2016) 1161-1165.
  • Sz. Ulenberg, M. Belka, T. Bączek, Comparison of MLR, OPLS, and SVM as potent chemometric techniques used to estimate in vitro metabolic stability, J. Chemometr., 30 (2016) 177-181.
  • L. Konieczna, K. Kaźmierska, A. Roszkowska, A. Szlagatys-Sidorkiewicz, T. Bączek, The LC-MS method for the simultaneous analysis of selected fat-soluble vitamins and their metabolites in serum samples obtained from pediatric patients with cystic fibrosis, J. Pharm. Biomed. Anal., 124 (2016) 374-381.
  • W. Hewelt-Belka, J. Nakonieczna, M. Belka, T. Bączek, J. Namieśnik, A. Kot-Wasik, Untargeted lipidomics reveals differences in the lipid pattern among clinical isolates of Staphylococcus aureus resistant and sensitive to antibiotics, J. Proteome Res., 15 (2016) 914-922.
  • K. Ciura, J. Nowakowska, K. Rudnicka-Litka, P. Kawczak, T. Bączek, M.J. Markuszewski, The study of salting-out thin-layer chromatography and their application on QSRR/QSAR of some macrolide antibiotics, Mon. Chem., 147 (2016) 301-310.
  • A. Hallmann, K. Smolarz, L. Konieczna, S. Zabrzańska, M. Belka, T. Bączek, LC-MS measurment of free steroids in mussels (Mytilus trossulus) from the southern Baltic Sea J. Pharm. Biomed. Anal., 117 (2016) 311-315.
  • J. Zielińska, M. Wieczór, T. Bączek, M. Gruszecki, J. Czub, Thermodynamics and kinetics of amphotericin B self-association in aqueous solution characterized in molecular detail [Dokument elektroniczny] Sci. Rep., 6 (2016) art. ID 19109, s. [1-11]
  • L. Konieczna, A. Roszkowska, A. Synakiewicz, T. Stachowicz-Stencel, E. Adamkiewicz-Drożyńska, T. Bączek, Analytical approach to determining human biogenic amines and their metabolites using eVol microextraction in packed syringe coupled to liquid chromatography mass spectrometry method with hydrophilic interaction chromatography column, Talanta 150 (2016) 331-339.
  • L. Konieczna, A. Roszkowska, M. Niedźwiecki, T. Bączek, Hydrophilic interaction chromatography combined with dispersive liquid–liquid microextraction as a preconcentration tool for the simultaneous determination of the panel of underivatized neurotransmitters in human urine samples, J. Chromatogr. A, 1431 (2016) 111–121.
  • A. Plenis, N. Rekowska, T. Bączek, Column Selection for Biomedical Analysis Supported by Column Classification Based on Four Test Parameters, Int. J. Mol. Sci., 17 (2016) (2), art. nr 136, s. 1-12 (doi:10.3390/ijms17010136)
2015
  • P. Žuvela, J.J. Liu, K. Macur, T. Bączek, Molecular descriptor subset selection in theoretical peptide quantitative structure-retention relationship model development using nature-inspired optimization algorithms, Anal. Chem., 87 (2015) 9876-9883.
  • P. Žuvela, J.J. Liu, A. Plenis, T. Bączek, Assessment of column selection systems using Partial Least Squares, J. Chromatogr. A 1420 (2015) 74-82.
  • A. Pogorzelska, J. Sławiński, K. Brożewicz, Sz. Ulenberg, T. Bączek, Novel 3-amino-6-chloro-7-(azol-2 or 5-yl)-1,1-dioxo-1,4,2-benzodithiazine derivatives with anticancer activity: synthesis and QSAR study, Molecules 20 (2015) 21960-21970.
  • B. Żołnowska, J. Sławiński, M. Belka, T. Bączek, A. Kawiak, J. Chojnacki, A. Pogorzelska, K. Szafrański, Synthesis, molecular structure, metabolic stability and QSAR studies of a novel series of anticancer N-acylbenzenesulfonamides, Molecules 20 (2015) 19101-19129.
  • N. Miękus, P. Kowalski, I. Olędzka, A. Plenis, E. Bień, A. Miękus, M. Krawczyk, E. Adamkiewicz-Drożyńska, T. Bączek, Cyclodextrin-modified MEKC method for quantification of selected acidic metabolites of catecholamines in the presence of various biogenic amines : application to diagnosis of neuroblastoma, J. Chromatogr. B 1003, (2015) 27-34.
  • I. Olędzka, Z. Kulińska, A. Prahl, T. Bączek, Simultaneous separation of eight benzodiazepines in human urine using field-amplified sample stracking micellar electrokinetic chromatography, J. Anal. Toxicol., 39, (2015) 436-443.
  • A. Gomółka, A. Ciesielska, M. Z. Wróbel, A. Chodkowski, J. Kleps, M. Dawidowski, A. Siwek, M. Wolak, K. Stachowicz, A. Sławińska, G. Nowak, G. Satała, A. J. Bojarski, M. Belka, Sz. Ulenberg, T. Bączek, P. Skowronek, J. Turło, F. Herold, Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. Part 5, Eur. J. Med. Chem. 98 (2015) 221-236.
  • A. Plenis, T.Bączek, J. Szulfer, M. Markuszewski, New materials applied for the stationary phases in view of the optimized HPLC and UHPLC column classification system used in the pharmaceutical analysis, Adv. Mater. Res. 1120-1121, (2015) 1404-1412.
  • J. Sławiński, B. Żołnowska, Z. Brzozowski, A. Kawiak, M. Belka, T. Bączek, Synthesis and QSAR study of novel 6-chloro-3(2-arylmethylene-1-methylhydrazino)-1,4,2-benzodithiazine 1,1-dioxide derivatives with anticancer activity, Molecules 20, (2015), 5754-5770.
  • Sz. Ulenberg, M. Belka, M. Król, F. Herold, W. Hewelt-Belka, A. Kot-Wasik, T. Bączek, Prediction of overall in vitro microsomal stability of drug candidates based on molecular modeling and support vector machines : case study of novel arylpiperazines derivatives, PLoS ONE 10, (2015) e0122772 [16] s. [Dokument elektroniczny]
  • S. Zabrzańska, K. Smolarz, A. Hallmann, L. Konieczna, T. Bączek, M. Wołowicz, Sex-related differences in steroid concentrations in the blue mussel (Mytilus edulis trossulus) from the southern Baltic Sea, Comp. Biochem. Physiol. A 183, (2015) 14-19.
  • J. Farkas, S. Bergum, E.W. Nilsen, A.J. Olsen, I. Salaberria, T.M. Ciesielski, T. Bączek, L. Konieczna, W. Salvenmoser, B.M. Jenssen, The impact of TiO2 nanoparticles on uptake and toxicity of benzo(a)pyrene in the blue mussel (Mytilus edulis), Sci. Total Environ., 511 (2015) 469-476.
  • P. Kawczak, L. Bober, T. Bączek, QSPR analysis of some agonists and antagonists of α-adrenergic receptors, Med. Chem. Res., 24, (2015) 372-382.
  • I. Olędzka, K. Kaźmierska, A. Plenis, B. Kamińska, T. Bączek, Capillary electromigration techniques as tools for assessing the status of vitamins A, C and E in patients with cystic fibrosis, J. Pharm. Biomed. Anal., 102 (2015) 45-53.
  • A. Chodkowski, M.Z. Wróbel, J. Turło, J. Kleps, A. Siwek, G. Nowak, M. Belka, T. Bączek, A.P. Mazurek, F. Herold, Novel 4-aryl-pyrido[1,2-c]pyrimidines with dual SSRI and 5-HT1A activity. Part 4, Eur. J. Med. Chem. 90, (2015) 21-32.
  • N. Miękus, I. Olędzka, A. Plenis, Z. Woźniak, A. Lewczuk, P. Koszałka, B. Seroczyńska, T. Bączek, Gel electrophoretic separation of proteins from cultured neuroendocrine tumor cell lines, Mol. Med. Rep. 11 (2015) 1407-1415.
2014
  • Sz. Dziomba, A. Bekasiewicz, A. Prahl, T. Bączek, P. Kowalski, Improvement of derivatized amino acid detection sensitivity in micellar electrokinetic capillary chromatography by means of acid-induced pH-mediated stacking technique, Anal. Bioanal. Chem., 406 (2014) 6713-6721.
  • W. Hewelt-Belka, J. Nakonieczna, M. Belka, T. Bączek, J. Namieśnik, A. Kot-Wasik, Comprehensive methodology for Staphylococcus aureus lipidomics by liquid chromatography and quadrupole time-of-flight mass spectrometry, J. Chromatogr. A 1362 (2014) 62-74.
  • M. Belka, W. Hewelt-Belka, J. Sławiński, T. Bączek, Mass spectrometry based identification of geometric isomers during metabolic stability study of a new cytotoxic sulfonamide derivatives supported by quantitative structure-retention relationships, PLoS ONE 9 (2014) nr 6, e98096.
  • T. Bączek, Modern LC in therapeutic drug monitoring and diagnosis of pediatric leukemia, Bioanalysis 6 (2014) 2897-2909.
  • P. Kawczak, L. Bober, T. Bączek, Biological activity of compounds exhibiting local anesthetic’s properties evaluated by QSAR approach, Curr. Pharm. Anal., 10 (2014) 255-262.
  • N. Miękus, T. Bączek, Phosphoproteomics as a promising tool for broadening the analysis of clinical samples and for the fight against cancer disease, Curr. Pharm. Anal. 10 (2014) 223-229.
  • P. Szatkowska, M. Koba, P. Kośliński, J. Wandas, T. Bączek, Analytical methods for determination of benzodiazepines. A short review, Cent. Eur. J. Chem. 12 (2014) 994-1007.
  • J. Szulfer, A. Plenis, T. Bączek, Comparison of core–shell and totally porous ultra high performanceliquid chromatographic stationary phases based on their selectivity towards alfuzosin compounds, J. Chromatography A, 1346 (2014) 69–77.
  • Sz. Dziomba, M. Biernacki, I.Olędzka, E. Skrzydlewska, T. Bączek, P. Kowalski, Repetitive injection field-amplified sample stacking for cationic compounds determination, Talanta 125 (2014) 1–6.
  • Sz. Dziomba, P. Kowalski, A. Słomińska, T. Bączek, Field-amplified sample injection coupled with pseudo-isotachophoresis technique for sensitive determination of selected psychiatric drugs in human urine samples after dispersive liquid-liquid microextraction, Anal. Chim. Acta 811 (2014) 88-93.
  • T. Bączek, R. Kaliszan, Podstawowe terminy farmakokinetyczne, w Biofarmacja pod red. M. Sznitowskiej, R. Kaliszana, Wrocław: Elsevier Urban & Partner, 2014
  • P. Kowalski, L. Konieczna, I. Olędzka, A. Plenis, T. Bączek, Development and validation of electromigration technique for the determination of lincomycin and clindamycin residues in poultry tissues, Food Anal. Meth., 7 (2014) 276-282.
  • I. Olędzka, P. Kowalski, A. Bałuch, Tomasz Bączek, Jolanta Paradziej-Łukowicz, M. Taciak, B. Pastuszewska, Quantification of the level of fat-soluble vitamins in feed based on the novel microemulsion electrokinetic chromatography (MEEKC) method, J. Sci. Food Agric., 94 (2014) 544-551.
  • A. Tuśnio, M. Taciak, M. Barszcz, J. Paradziej-Łukowicz, I. Olędzka, W. Wiczkowski, M. Szumska, B. Pastuszewska, J. Skomiał, Thermal sterilization affects the content of selected compounds in diets for laboratory animals, J. Anim. Feed Sci., 23 (2014) 351-360.

2013

  • Sz. Dziomba, P. Kowalski, I. Olędzka, T. Bączek, Wzbogacanie analitu w kapilarze w wysokosprawnych technikach elektromigracyjnych – spiętrzanie, Analityka 14 (2013) 18-25.
  • N. Miękus, T. Bączek, Fosfoproteomika – perspektywa bardziej precyzyjnych badań biomedycznych,Farm. Pol., 69 (2013) 716-723.
  • P. Kowalski, T. Bączek, Tosylany oraz inne pochodne kwasów sulfonowych : ich znaczenie w nowoczesnej farmacji, Farm. Pol., 69 (2013) 550-557.
  • A. Chmielewska, Z żałobnej kartoteki: Henryk Lamparczyk (1947-2012)_Ann. Acad. Med. Gedan._ 43 (2013) 251-254
  • H. Lamparczyk, A. Chmielewska, P.K. Zarzycki, Short review of cyclodextrins applications in separation science focusing on pharmaceutical, biomedical and enviromental analysis, Camera Separat. 5 (2013) 39-51.
  • I. Olędzka, 24thInternational Symposium on Pharmaceutical and Biomedical Analysis, PBA 2013 30 czerwca – 3 lipca 2013, Bolonia, Włochy, Farm. Pol., 69 (2013) 584-586.
  • Sz. Dziomba, M. Belka, P. Kowalski, A. Plenis, T. Bączek, The advances of electromigration techniques applied for alkaloid analysis, Biomed. Chromatogr., 27 (2013) 1312-1338.
  • J. Stasiak, M. Koba, L. Bober, P. Kawczak, T. Bączek, The comparison between the calculated and HPLC-predicted lipophilicity parameters for selected groups of drugs,Comb. Chem. High Throughput Screen., 16 (2013) 603-617.
  • I. Olędzka, A. Bączek, J. Pańko, T. Bączek, Development and validation of the MEKC method for a stability indicating assay of midazolam in pediatric syrup, Curr. Pharm. Anal., 9 (2013) 347-354.
  • P. Kowalski, T. Bączek, Tosylany oraz inne pochodne kwasów sulfonowych: ich znaczenie w nowoczesnej farmacji,Farm. Pol., 69 (2013) 550-55.
  • M. Koba, T. Bączek, The evaluation of multivariate adaptive regression splines for the prediction of antitumor activity of acridinone derivatives,Med. Chem., 9 (2013) 1041-1050.
  • Alina Plenis, N. Miękus, I. Olędzka, T. Bączek, A. Lewczuk, Z. Woźniak, P. Koszałka, B. Seroczyńska, J. Skokowski, Chemometric evaluation of urinary steroid hormone levels as potential biomarkers of neuroendocrine tumors, Molecules, 18 (2013) 12857-12876.
  • I. Olędzka, P. Kowalski, Sz. Dziomba, P. Szmudanowski, T. Bączek, Optimization of a pre-MEKC separation SPE procedure for steroid molecules in human urine samples,Molecules, 18 (2013) 14013-14032.
  • T. Bączek. LC-MS and chemometrics for steroid biomarker profiles in view of the future diagnostics of diseases.Bioanalysis, 5, (2013) 1347-1351
  • L. Konieczna, M. Belka, T. Bączek, M. Ruszkowski, W. Struck, M. Markuszewski, R. Kaliszan, M.Markuszewski. Advanced assessment of the endogenous hormone level as a potential biomarker of the urogenital tract cancer.Comb. Chem. High Throughput Screen. 16, (2013) 463-472.
  • L. Konieczna, J. Skokowski, I. Olędzka, K. Macur, M. Belka, T. Bączek, W. Struck, M. Markuszewski, The osteopontin tissue level as a breast cancer biomarker in females after mastectomy measured by the capillary gel electrophoresis technique,Comb. Chem. High Throughput Screen., 16 (2013) 331-338.
  • J. Szulfer, A. Plenis, T. Baczek. Chemometric evaluation of the column classification system during the pharmaceutical analysis of lamotrigine and its related substances.Anal. Bioanal. Chem., 405, (2013) 6529–6541.
  • J. Kumirska, A. Plenis, P. Łukaszewicz, M. Caban, N. Migowska, A. Białk-Bielińska, M. Czerwicka, P. Stepnowski, Chemometric optimization of derivatization reactions prior to gas chromatography–mass spectrometry analysis, J.Chromatogr. A, 1296 (2013) 164-178.
  • M. Belka, J. Sławiński, L. Konieczna, P. Kawczak, M. Ciesielski, T. Bączek, Antitumor activity of novel benzensulfonamide derivatives in view of their physiochemical properties searched by principal component analysis,Med. Chem., 9 (2013) 517-525.
  • A. Plenis, I. Olędzka, T. Bączek, Classification of LC columns based on the QSRR method and selectivity toward moclobemide and its metabolites, J. Pharm. Biomed. Anal., 78-79 (2013) 161-169.
  • L. Konieczna, T. Bączek, M. Belka, A. Fel, M. Markuszewski, W. Struck, M. Markuszewski, R. Kaliszan, Steroid profiles as potential biomarkers in patients with urogenital tract cancer for diagnostics investigations analyzed by liquid chromatography coupled to mass spektrometry, J. Pharm. Biomed. Anal., 73 (2013) 108-115.
  • A. Plenis, L. Konieczna, N. Miękus, T. Bączek, Development of the HPLC method for simultaneous determination of lidocaine hydrochloride and tribenoside along with their impurities supported by the QSRR approach, Chromatographia 76 (2013) 255-265.
  • M. Wnuk, M. P. Marszałł, A. Zapęcka, A. Nowaczyk, J. Krysiński, J. Romaszko, P. Kawczak, T. Bączek, A. Buciński, Prediction of antimicrobial activity of imidazole derivatives by artificial neural networks, Centr. Eur. J. Med., 8 (2013) 1-15.
  • M. Koba, M.P. Marszałł, W. Sroka, M. Tłuchowska, T. Bączek, Determination of lamotrigine in tablets using HPTLC, HPLC and derivative spectrophotometry methods, J. Liq. Chrom. Rel. Technol., 36 (2013) 537-548.
  • M. Koba, A. Słomka, T. Bączek, M. P. Marszałł, E. Żekanowska, Ability to determine the desferrioxamine-chelatable iron fractions of nontransferrin-bound iron using HPLC, J. Sep. Sci., 36 (2013) 665-669.
2012
  • Sz. Dziomba, P. Kowalski, T. Bączek, Field-amplified sample stacking-sweeping of vitamins B determination in capillary electrophoresis, J. Chromatogr. A, 1267 (2012) 224-230.
  • T. Bączek, L. Konieczna, M. Belka, L. Maciejka-Kapuścińska, J. Wiśniewski, M. Niedźwiecki, A. Balcerska, E. Adamkiewicz-Drożyńska, J. Wachowiak, Topotecan exposure estimation in pediatric acute myeloid leukemia supported by LC-MS-based drug monitoring and pharmacokinetics analysis, J. Pharm. Biomed. Anal., 70 (2012) 330-336.
  • J. Szulfer, A. Plenis, T. Bączek, Application of a column classification method in a selectivity study involving caffeine and its related impurities, Talanta, 99 (2012) 492-501.
  • M. Koba, T. Bączek, Importance of some classes of molecular descriptors on classification of antitumor acridinones using factor analysis, Med. Chem. Res., 21 (2012) 2854-2862.
  • M. Koba, T. Bączek, T. Ciesielski, Influence of LC retention data on antitumor acridinones’ classification evaluated by factor analysis method, Comb. Chem. High Throughput Screen., 15 (2012) 674-683.
  • A. Szlagatys-Sidorkiewicz, M. Zagierski, G. Łuczak, K. Macur, T. Bączek, B. Kamińska, Maternal smoking does not influence vitamin A and E concentrations in mature breast milk, Breastfeed. Med., 7 (2012) 285-289.
  • I. Olędzka, P. Kowalski, T. Bączek, B. Muszyńska-Furas, J. Paradziej-Łukowicz, M. Taciak, B. Pastuszewska, Determination of water soluble vitamins in laboratory animal feeds by micellar electrokinetic chromatography, Anal. Lett., 45 (2012) 689-701.
  • M. Koba, M. Belka, T. Ciesielski, T. Bączek, Determination of lipophilicity for antitumor acridinone derivatives supported by gradient high-performance liquid chromatography method, Centr. Eur. J. Chem., 10 (2012) 216-223.
  • P. Kawczak, T. Bączek, Recent theoretical and practical applications of micellar liquid chromatography (MLC) in pharmaceutical and biomedical analysis, Centr. Eur. J. Chem., 10 (2012) 570-584.
  • M. Koba, T. Bączek, The influence of lipophilicity on the classification of antitumor acridinones evaluated by principal component analysis, Curr. Pharm. Anal., 8 (2012) 157-174.
  • A. Szlagatys-Sidorkiewicz, M Zagierski, A. Jankowska, G. Łuczak, K. Macur, T. Bączek, M. Korzon, G. Krzykowski, D. Martysiak-Żurowska, B. Kamińska, Longitudinal study of vitamins A, E and lipid oxidative damage in human milk throughout lactation, Early Hum. Dev., 88 (2012) 421-424.
  • L. Bober, P. Kawczak, T. Bączek, Pharmacological classification and activity evaluation of furan and thiophene amide derivatives applying semi-empirical ab initio molecular modeling methods, Int. J. Mol. Sci., 13 (2012) 6665-6678.
  • L. Konieczna, L. Bober, M. Belka, T. Ciesielski, T. Bączek, Chemometric exploration of the dependencies between molecular modeling descriptors and analytical chemistry data of antihistaminic drugs, J. AOAC Int., 95 (2012) 713-723.
  • A. Chmielewska, T. Bączek, Comparative analysis of chiral drugs in view of chemometrics, J. AOAC Int., 95 (2012) 624-635.
  • J. Szulfer, A. Plenis, T. Bączek, Evaluation of a column classification method using the separation of alfuzosin from its related substances, J. Chromatogr. A 1229 (2012) 198-207.
  • M. Koba, T. Bączek, M. P. Marszałł, Importance of retention data from affinity and reverse-phase high-performance liquid chromatography on antitumor activity prediction of imidazoacridinones using QSAR strategy, J. Pharm. Biomed. Anal., 64-65 (2012) 87-93.
  • Sz. Dziomba, P. Kowalski, T. Bączek, Micelle to solvent stacking of tricyclic psychiatric drugs in capillary electrophoresis, J. Pharm. Biomed. Anal. 62 (2012) 149-154.
  • M. Belka, L. Konieczna, P. Kawczak, T. Ciesielski, J. Sławiński, T. Bączek, The chemometric evaluation of antitumor activity of novel benzensulfonamide derivatives based on their physiochemical properties, Lett. Drug Des. Discov., 9 (2012) 288-294.
  • L. Bober, P. Kawczak, T. Bączek, QSAR analysis of compounds exhibiting general anesthetics’ properties, Lett. Drug Des. Discov., 9 (2012) 595-603.
  • I. Olędzka, K. Włodarski, J. Paradziej-Łukowicz, T. Bączek, Comparative evaluation of tissue protein separations applying one-dimensional gel electrophoresis and capillary gel electrophoresis, Open Proteomics J. 5, (2012) 17-21.
  • T. Bączek, I. Olędzka, L. Konieczna, P. Kowalski, A. Plenis, Biomedical evaluation of cortisol, cortisone and corticosterone along with testosterone and epitestosterone applying micellar electrokinetic chromatography [dokument elektroniczny] Sci. World J., (2012) art. nr 268120.
  • Z. Wojnarowska, K. Grzybowska, L. Hawelek, A. Swiety-Pospiech, E. Masiewicz, M. Paluch, W. Sawicki, A. Chmielewska, P. Bujak, J. Markowski, Molecular dynamics studies on the water mixtures of pharmaceutically important ionic liquid lidocaine HCl, Mol. Pharm., 9 (2012) 1250-1261.

2011

  • A. Plenis, E. Balakowska, T. Bączek, The comparison of two column classification systems during the chromatographic analysis of steroids, J. Sep. Sci., 34 (2011) 3310-3321.
  • L. Bober, M. Koba, U. Judycka-Proma, T. Bączek, Pharmacological classification of drugs by principal component analysis applying molecular modeling descriptors and HPLC retention data, J. Chromatogr. Sci., 49 (2011) 758-763.
  • M. Koba, T. Bączek, Mechanisms of action of imidazoacridinone and triazoloacridinone derivatives in view of their biological activity, Curr. Pharm. Anal., 7 (2011) 286-295, review.
  • M. Koba, T. Bączek, Physicochemical interaction of antitumor acridinone derivatives with DNA in view of QSAR studies, Med. Chem. Res., 20 (2011) 1385-1393.
  • P. Kowalski, I. Olędzka, A. Plenis, T. Bączek, Elektroforetyczne oznaczanie kationów: sodu, potasu, wapnia i magnezu w butelkowanych wodach mineralnych, Bromat. Chem. Toksykol., 3 (2011) 347-350.
  • A. Chmielewska, L. Konieczna, H. Lamparczyk, determination of enrofloxacin in animal plasma samples by RP-HPLC method with fluorescence detection, Bromat. Chem. Toksykol., 3 (2011) 742-747.
  • A. Plenis, L. Konieczna, I. Olędzka, P. Kowalski, T. Bączek, Simultaneous determination of urinary cortisol, cortisone and corticosterone in parachutists, depressed patients and healthy controls in view of biomedical and pharmacokinetic studiem, Mol. BioSyst., 7 (2011) 1487-1500.
  • L. Konieczna, A. Plenis, I. Olędzka, P. Kowalski, T. Bączek, Optimization of LC method for the determination of testosterone and epitestosterone in urine samples in view of biomedical studies and anti-doping research studies, Talanta, 83 (2011) 804–814.
  • P. Kowalski, A. Plenis, I. Olędzka, L. Konieczna, Optimization and validation of the micellar electrokinetic capillary chromatographic method for simultaneous determination of sulfonamide and amphenicol-type drugs in poultry tissue, J. Pharm. Biomed. Anal., 54 (2011) 160-167.
  • A. Plenis, T. Bączek, Modern chromatographic and electrophoretic measurements of antidepressants and their metabolites in biofluids, Biomed. Chromatogr., 25 (2011) 164-198.
  • M. Koba, K. Koba, T. Bączek, UV-densitometric HPTLC method for analysis of nitrazepam in pharmaceutical formulations, J. Planar Chromatogr., 24 (2011) 44-47.
  • J. Kumirska, N. Migowska, M. Caban, A. Plenis, P. Stepnowski, Chemometric analysis for optimizing derivatization in gas chromatography-based procedures, J. Chemometrics, 25 (2011) 636–643.

2010

  • M. Koba, T. Bączek, K. Macur, L. Bober, T. Frąckowiak, A. Buciński, D. Rystok-Grabska, J. Stasiak, K. Koba, Factor analysis of microbiological activity data and structural parameters of antibacterial quinolones, J. Mol. Model., 16 (2010) 327-335.
  • M. Ostrowski, E. Wilkowska, T. Bączek, Impact of pharmaceutical dosage form on stability and dissolution of roxithromycin, Cent. Eur. J. Med., 5 (2010) 83-90.
  • K. Macur, T. Bączek, R. Kaliszan, C. Temporini, F. Corana, G. Massolini, J. Grzenkowicz-Wydra, M. Obuchowski, Correctness of protein identifications of Bacillus subtilis proteome with the indication on potential false positive peptides supported by predictions of their retention times, J. Biomed. Biotechnol., 2010 (2010) 718142.
  • P. Kawczak, Y. Vander Heyden, A. Nasal, T. Bączek, A. Drabczyńska, K. Kieć-Kononowicz, R. Kaliszan, Micellar liquid chromatography for lipophilicity determination of new biologically active 1,3-purinodiones, J. Sep. Sci., 33 (2010) 1546-1557.
  • L. Konieczna, A. Plenis, I. Olędzka, P. Kowalski, T. Bączek, Development and validation of liquid chromatography method with fluorescence detection for the determination of fexofenadine in human plasma in view of pharmacokinetics studies, Chromatographia, 71 (2010) 1081-1086.
  • J. Stasiak, M. Koba, L. Bober, T. Bączek, Principal component analysis of HPLC retention data and molecular modeling structural parameters of cardiovascular system drugs in view of their pharmacological activity, Int. J. Mol. Sci., 11 (2010) 2681-2698.
  • A. Chmielewska, L. Konieczna, A. Plenis, T. Bączek, H. Lamparczyk, Rapid and sensitive RP-LC method with amperometric detection for pharmacokinetic assessment of propafenone in human serum of healthy volunteers, J. Anal. Chem., 65 (2010) 1164-1169.
  • M. Koba, J. Stasiak, L. Bober, T. Bączek, Evaluation of the molecular and HPLC retention data of analgesic and anti-inflammatory drugs by factor analysis in view of their pharmacological activity, J. Mol. Mod., 16 (2010) 1319-1331.
  • I. Olędzka, A. Plenis, L. Konieczna, P. Kowalski, T. Bączek, Micellar electrokinetic chromatography for the determination of cortisol in urine samples in view of biomedical studies, Electrophoresis, 31 (2010) 2356-2364.
  • A. Plenis, L. Konieczna, I. Olędzka, P. Kowalski, Rapid analysis of loratadine in human serum by high-performance liquid chromatography with fluorescence detection, Acta Chromatogr., 22 (2010) 69-79.
  • I. Olędzka, T. Bączek, Urinary steroids measured by modern separation techniques applied as biomarkers in stress studies, Curr. Pharm. Anal., 6 (2010) 151-163.
  • L. Konieczna, T. Bączek, Plasma steroid level measured using modern separation techniques as biomarkers in biological diagnostics, Curr. Pharm. Anal., 6 (2010) 164-181.
  • A. Plenis, T. Bączek, Quantification of salivary steroid hormones considered as biomarkers in clinical and anti-doping research studies, Curr. Pharm. Anal., 6 (2010) 182-197.
  • M. Koba, L. Bober, U. Judycka-Proma, T. Bączek, Influence of HPLC retention data and molecular modeling descriptors on prediction of pharmacological classification of drugs using factor analysis method, Comb. Chem. High Throughput Screen., 13 (2010) 765-776.
  • M. Ostrowski, E. Wilkowska, T. Bączek, The influence of averaging procedure on the accuracy of IVIVC predictions: immediate release dosage form case study, J. Pharm. Sci., 99 (2010) 5040-5045.
  • M. Ostrowski, T. Bączek, The progress on the in vivo-in vitro correlation (IVIVC) for immediate release dosage form as an alternative to bioavailability studies, Curr. Pharm. Anal., 6 (2010) 289-298.
  • B. Sparzak, M. Merino-Arevalo, Y. Vander-Heyden, M. Krauze-Baranowska, M. Majdan, I. Fecka, D. Głód, T. Bączek, HPLC analysis of polyphenols in the fruits of Rubus idaeus L. (Rosaceae), Nat. Prod. Res., 24 (2010) 1811-1822.
  • L. Konieczna, A. Plenis, I. Olędzka, P. Kowalski, T. Bączek, Simultaneous determination of cortisol, cortisone and corticosterone in human plasma of parachutists in view of pharmacokinetics studies, J. Liq. Chromatogr. Relat. Technol., 33 (2010) 1613-1629.
  • K. Macur, C. Temporini, G. Massolini, J. Grzenkowicz-Wydra, M. Obuchowski, T. Bączek, Proteomic analysis of small acid soluble proteins in the spore core of Bacillus subtilis ΔprpE and 168 strains with predictions of peptides liquid chromatography retention times as an additional tool in protein identification, Proteome Science, 8 (2010) 1-8.
Aktualizacja strony: 29.05.2019
Piotr Kawczak, Alina Plenis